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The authors concluded that botulinum toxin appears relatively safe and effective in treating cervical dystonia and chronic facial pain associated with masticatory hyperactivity.
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They stated that this finding opened the door to further clinical research.
Prospective data including tinnitus matching test, tinnitus handicap inventory (THI), tinnitus rating scale (TRS), and patient questionnaires were obtained over a 4-month period after each injection.
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The secondary outcome was the change in foot function, which was assessed using the Foot Health Status Questionnaire.
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The primary outcomes measured were the healing of the anal fissure and the development of incontinence as the major adverse event during the 1-year follow-up period.
Treatment with injections of type A botulinum toxin was conducted in association with a splint and relaxation.
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Fried and Fried (2003) noted that spasticity is commonly seen after spinal cord injury (SCI), and a large percentage of patients with SCI will need treatment to control it.
Each treatment lasts approximately 3 months, after which the procedure can be repeated.
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Patients were followed for 1 year to assess maintenance of sinus rhythm using an implantable loop recorder (ILR).
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NRS during the screening phase for worst anal pain associated with, or following, defaecation for the most recent 3 days on which the subject has defaecated.
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Life-threatening sepsis following treatment for haemorrhoids: a systematic review.
The pain subsided after only 48hours of using only wheatgrass cream 3 times a day.
Fregene et al (2009) performed a retrospective chart review on the use of botulinum toxin type A (botulinum toxin A) for the treatment of digital ischemia in patients with Raynaud`s phenomenon.
The safety and efficacy of REXULTI has not been established in pediatric patients with depression.
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Care is taken not to cut the anal mucosa, because doing so could result in a fistula.
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At the 4-week post-injection stage, improvement in sleep quality was measured using the Chinese version of the Pittsburgh Sleep Quality Index.
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These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.
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Clinical variables including age, sex, site and size of the lesion, standing activity, weekly duration of walking, footwear, foot type and footprint had no influence on the outcome.
The findings of this study were in agreement with those of Mathews et al (2005).
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Click on citations within drug and disease topics in our clinical reference to review the clinical evidence on MEDLINE.
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In one study, 155 children aged 2 - 18 years with cerebral palsy and exhibiting equinus foot deformity received IM injections of botulinum toxin type A for at least 1 year.
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Women using oral contraception must have started using it at least 2 months prior to enrolment.
AIMS To investigate the effect of oral and topical calcium channel blockade and a topical cholinomimetic on anal sphincter pressure.
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SIGLE (System for Information on Grey Literature in Europe) were searched from January 1990 to April 2011 for RCTs or non-randomized studies assessing the effectiveness of botulinum toxins on bruxism.
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They attempted to contact researchers who are active in this field for information about further published or unpublished studies.
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Botulinum toxin type A (BOTOX) for the prophylactic treatment of chronic daily headache: A randomized, double-blind, placebo-controlled trial.
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The findings suggested that there is level-1 evidence supporting the efficacy of Botox in the treatment of spasmodic dysphonia, essential voice tremor, headache, cervical dystonia, masticatory myalgia, sialorrhea, temporo-mandibular joint disorders, bruxism, blepharospasm, hemi-facial spasm and rhinitis.
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